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. 2020 Mar 11;10:217. doi: 10.3389/fonc.2020.00217

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Copyright © 2020 Meng, Wang, Zhao, Hu, Zhi, Wei, Ruan, Hou, Li, Zhang, Yang, Qian, Wu, Zhang, Meng, Guan, Zhang, Zheng and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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VEGFR2 expression is elevated in PTC. (A) Immunohistochemical staining of a TMA containing PTC and normal thyroid follicular tissue specimens for VEGFR2. (B) VEGFR2 expression in PTC and normal thyroid follicular tissue. (C) VEGFR2 mRNA levels in PTC and normal thyroid follicular tissue. (D) Western blot assay showing increased VEGFR2 expression in PTC tissue compared to normal thyroid tissue. (E) Western blot assay of VEGFR2 expression in thyroid cell lines. (F) VEGFR2 mRNA levels in thyroid cell lines. Data are expressed as the mean ± SD (*P < 0.05, **P < 0.01, ***P < 0.001 vs. N9 cells).