Table 2.

Correlation of histomorphological parameters and cellular dissociation grade with clinicopathological data.

	Cell Nest Size					Budding activity				Grading
	Large	Intermediate	Small	Single-cell invasion	p-value	Absent	Low	High	p-value	nG1	nG2	nG3	p-value
Age
Median and below	6	11	28	35	0.589	17	43	20	0.927	17	44	19	0.981
Above median	10	7	27	36		17	45	18		17	45	18
Gender
Male	13	18	41	57	0.131	31	66	32	0.104	31	67	31	0.117
Female	3	0	14	14		3	22	6		3	22	6
cT stage
1	3	1	11	1	0.017	4	11	1	0.059	4	11	1	0.100
2	3	5	12	12		8	21	3		8	21	3
3	3	2	6	12		5	9	9		5	10	8
4a/b	1	3	6	19		4	15	10		4	15	10
cN stage
0	4	6	18	12	0.010	10	23	7	0.447	10	23	7	0.404
1	1	4	6	4		5	7	3		5	8	2
2	5	1	9	28		6	24	13		6	24	13
3	0	0	2	0		0	2	0		0	2	0
Pre-therapeutic UICC stage
I	2	1	8	0	0.073	3	8	0	0.142	3	8	0	0.231
II	1	3	6	5		4	10	1		4	10	1
II	2	3	7	9		5	8	8		5	9	7
Iva/b	5	4	14	30		9	30	14		9	30	14
pT stage
1	7	4	19	7	0.001	11	23	3	0.002	11	23	3	0.002
2	2	8	18	24		10	32	10		10	33	9
3	6	4	3	19		10	9	13		10	9	13
4a/b	1	2	15	21		3	24	12		3	24	12
pN stage
0	12	12	31	18	<0.001	24	39	10	0.001	24	39	10	0.001
1	2	2	9	13		4	16	6		4	17	5
2	2	4	14	40		6	32	22		6	32	22
3	0	0	1	0		0	1	0		0	1	0
Post-therapeutic UICC stage
I	7	3	15	3	0.001	10	16	2	0.003	10	16	2	0.005
II	1	4	5	6		5	11	0		5	11	0
II	5	5	9	17		10	15	11		10	16	10
Iva/b	3	6	26	45		9	46	25		9	46	25
Recurrence
No recurrence	14	16	28	36	0.248	30	47	17	0.321	30	47	17	0.394
Local recurrence	1	2	11	8		3	14	5		3	14	5
Nodale recurrence	0	0	5	1		0	6	0		0	6	0
Distant recurrence	1	0	4	15		1	11	8		1	11	8
Combined recurrence	0	0	6	9		0	8	7		0	9	6
Recurrence; localisation unclear	0	0	1	2		0	2	1		0	2	1

The values given in italics are the p-values obtained in statistical analysis for the respective correlations