Table 3.
Multivariate survival analysis including Cellular Dissociation Grade, age, gender and post-operative UICC stage.
| Hazard ratio | Confidence interval | p-value | ||
|---|---|---|---|---|
| HR | Low | High | ||
| Overall survival | ||||
| Gender | ||||
| Male | 1.000 | 0.160 | ||
| Female | 0.625 | 0.325 | 1.204 | |
| Age | ||||
| Median and below | 1.000 | 0.022 | ||
| Above median | 1.764 | 1.087 | 2.880 | |
| UICC stage | ||||
| I | 1.000 | 0.008 | ||
| II | 0.298 | 0.034 | 2.574 | |
| III | 2.043 | 0.740 | 5.644 | |
| Iva/b | 3.194 | 1.250 | 8.164 | |
| Cellular Dissociation Grade | ||||
| nG1 | 1.000 | 0.004 | ||
| nG2 | 2.500 | 1.078 | 5.797 | |
| nG3 | 4.222 | 1.771 | 10.065 | |
| Disease-specific survival | ||||
| Gender | ||||
| Male | 1.000 | 0.417 | ||
| Female | 0.750 | 0.375 | 1.502 | |
| Age | ||||
| Median and below | 1.000 | 0.054 | ||
| Above median | 1.717 | 0.991 | 2.973 | |
| UICC stage | ||||
| I | 1.000 | 0.046 | ||
| II | <0.001 | <0.001 | >100.0 | |
| III | 7.462 | 0.962 | 57.875 | |
| Iva/b | 12.382 | 1.690 | 90.713 | |
| Cellular Dissociation Grade | ||||
| nG1 | 1.000 | 0.002 | ||
| nG2 | 6.131 | 1.426 | 26.361 | |
| nG3 | 11.095 | 2.565 | 47.999 | |
| Disease-free survival | ||||
| Gender | ||||
| Male | 1.000 | 0.486 | ||
| Female | 0.802 | 0.431 | 1.492 | |
| Age | ||||
| Median and below | 1.000 | 0.130 | ||
| Above median | 1.478 | 0.892 | 2.451 | |
| UICC stage | ||||
| I | 1.000 | 0.136 | ||
| II | 1.123 | 0.336 | 3.751 | |
| III | 1.452 | 0.543 | 3.883 | |
| Iva/b | 2.245 | 0.939 | 5.364 | |
| Cellular Dissociation Grade | ||||
| nG1 | 1.000 | 0.002 | ||
| nG2 | 5.002 | 1.746 | 14.336 | |
| nG3 | 7.393 | 2.456 | 22.260 | |
The values in italics represent the p-values for the respective statistical analysis