Fig. 3. Hydrophobic N370 mutants have wt-like S4 movement but do not close completely.

Representative current (black) and fluorescence (red) from a N370G^*, b N370A^*, c N370V^*, d N370I^*, and e N370E^* channels. Scale bars: 0.1 s, 5 µA, and 0.5% ΔF/F. f, g Normalized f G(V) and g F(V) curves of wt^*, N370G^*, N370A^*, N370V^*, N370I^*, N370D^*, and N370E^* channels. Mean ± SEM. Source data are provided as a Source Data file.