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Comparison of the area fraction of Aβ42 (A), area fraction of Iba1 (B), and area fraction ratio of Iba1 against Aβ42 (C) in the hippocampus among the three groups of the mice. The hippocampal sections with immunohistochemical staining were analyzed by ImageJ. WT, wild type C57BL/6J mice; AppNL-G-F, AppNL-G-F/NL-G-F mice; Ctrl, control-fed group; AX, astaxanthin-fed group. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
