Fig. 2.

Biliary function during 4 h of normothermic reperfusion.

(A) Cumulative bile production during reperfusion, (B) biliary pH, (C) biliary bicarbonate at the end of reperfusion, (D) biliary LDH at the end of reperfusion. All livers show good biliary function after preservation for either 2 h, 6 h, or 24 h of DHOPE and there were no significant differences between the groups in all parameters shown (Kruskal-Wallis test). (E) Histology of extrahepatic bile ducts, ∗ = bile duct lumen, arrow = absence of luminal epithelium. Shown here are the mean and SEM for n = 6 livers per group. DHOPE, dual hypothermic oxygenated machine perfusion; LDH, lactate dehydrogenase.