Fig. 3.

Markers for cellular injury at the end of normothermic reperfusion.

Perfusate levels of (A) ALT (p = 0.687), (B) HMGB-1 (p = 0.690), (C) and cfDNA (p = 0.229). There were no statistically significant differences between the groups at the end of reperfusion (Kruskal-Wallis test). (D) percentage of necrosis on histological analysis of liver parenchyma after H&E staining, (p = 0.396) (E) H&E staining of liver parenchyma. Shown here are the mean and SEM for n = 6 livers per group. ALT, alanine aminotransferase; cfDNA, cell-free DNA; DHOPE, dual hypothermic oxygenated machine perfusion; HMGB-1, high-mobility group 1; SCS, static cold storage.