Blockage of Lipid Metabolism Suppressed Cell Survival under Stress
(A) Time-dependent MIA PaCa-2 cell viability with and without chloroquine sulfate treatment, atglistatin treatment, and etomoxir treatment under starvation condition. The bars indicate means ± SEM.
(B) Gemcitabine concentration-dependent G3K cell viability with and without chloroquine sulfate treatment, atglistatin treatment, and etomoxir treatment for 72 h. The bars indicate means ± SEM.
(C–E) Concentration-dependent MIA PaCa-2 cell viability for cells treated by (C) chloroquine sulfate, (D) atglistatin, and (E) etomoxir under normal and starved conditions for 24 h. The bars indicate means ± SEM.
(F–H) Concentration-dependent viability for MIA PaCa-2 cells and G3K cells, treated by (F) chloroquine sulfate, (G) atglistatin, and (H) etomoxir, for 72 h, n = 3. The bars indicate means ± SEM.