Fig. 1.

Dose effect of oral B12 intake on plasma and kidney B12 content. B12 was administered to WT male mice via drinking water for 5 days and dose per day was calculated as 4 ml of water intake. A) plasma concentration of B12. B) B12 level in kidneys. n ≥ 5. *p < 0.05, **p < 0.01 by Tukey–Kramer Honest Significant Difference test. Error bars indicate group mean ± SEM.