TABLE 4.
Top 20 classifier genes that discriminate subjects with acute LD from healthy controls
| Gene symbol | Gene title | RFIL (%)a |
|---|---|---|
| PSMB8 | Protease subunit β8 | 9.14 |
| SLAMF7 | SLAM family member 7 | 7.58 |
| RAB24 | RAB24, member RAS oncogene family | 7.11 |
| FCGR1B | Fc fragment of IgG, high affinity 1b, receptor (CD64) | 6.52 |
| MPP1 | Membrane protein, palmitoylated 1, 55 kDa | 5.86 |
| CSF2RB | Colony stimulating factor 2 receptor, beta, low affinity (granulocyte-macrophage) |
5.55 |
| TNFSF10 | Tumor necrosis factor (ligand) superfamily, member 10 | 4.75 |
| BTG1 | B-cell translocation gene 1, antiproliferative | 4.72 |
| GPR183 | G protein-coupled receptor 183 | 4.54 |
| ATG16L2 | Autophagy-related 16-like 2 | 4.50 |
| ACOT7 | Acyl-CoA thioesterase 7 | 4.37 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting V0 subunit a3 |
4.25 |
| CHKB_CPT1B | CHKB-CPT1B readthrough (NMD candidate) | 4.20 |
| DYNLL1 | Dynein light chain LC8-type 1 | 4.13 |
| LCN2 | Lipocalin 2 | 4.05 |
| HSPA6_HSP70B′ | Heat shock protein family A (Hsp70) member 6 | 4.02 |
| FCGR1A | Fc fragment of IgG, high-affinity 1a, receptor (CD64) | 3.85 |
| RCAN3 | RCAN family member 3 (calcipressin 3) | 3.74 |
| HK3 | Hexokinase 3 | 3.65 |
| AP1G2 | Adaptor-related protein complex 1 γ2 subunit | 3.48 |
| Total | 100 |
a
RFIL, random forest importance level.