FIG 6.

Host IFN-γ can synergize with IFN-γ produced by NR1 T cells to mediate enhanced bacterial clearance. WT B6 mice received 10⁶ Th1-skewed WT or IFN-γ^−/− RFP NR1 T cells 1 day prior to infection with 5 × 10⁶ IFU C. trachomatis. Five days postinfection, upper genital tracts were harvested and bacterial burden was assessed by qPCR. Data were pooled from results of two independent experiments performed with at least five mice per group and were analyzed using unpaired t test. *, P < 0.05.