TABLE 3.

Extracellular proteases of P. aeruginosa and their regulation by RpoS

Gene no.	Gene name and product description	RpoS regulationa	Reference
PA0423	pasP, small protease	None	69
PA1249	aprA, alkaline metalloproteinase precursor	−1.7	70
PA1871	lasA, LasA protease precursor	None	71
PA2939	pepB, aminopeptidase PaAP	140	25
PA3724	lasB, LasB elastase, neutral metalloproteinase	None	71
PA4175	piv (prpL), protease IV	6.8	35
PA4541	lepA, large extracellular protease	None	72

^aFold change in gene expression of WT strain versus rpoS mutant (11). Downregulation is indicated with a minus sign.