Table 3.

Patients' detailed characteristics

Patient number	Age at diagnosis	Gender	Alive	Response by RANO 1.1	IDH-1/2	MGMT Promoter Methylation Status	Tumor Location	KPS Status	Surgery before ChemoID	Repeat Surgical Resection after ChemoID/Biopsy	LITT before ChemoID	LITT after ChemoID	Irradiation before ChemoID	Irradiation after ChemoID
1	32	M	No	PR	Wild-type	Methylated	Left Frontal, Multifocal	80	Yes	No	Yes	No	Yes	No
2	60	F	No	PD	Wild-type	Unmethylated	Right frontal, Multifocal	70	No	Yes (for infection)	No	No	No	No
3	49	F	No	CR	Wild-type	Unmethylated	Right Temporal	80	Yes	No	No	No	No	Yes
4	60	M	No	PD	Wild-type	Unmethylated	Left Temporal	70	Yes	No	No	No	No	No
5	48	M	Yes	CR	Wild-type	Unmethylated	Right Frontal	60	Yes	No	No	No	Yes	No
6	49	F	No	CR	Mutant	Unmethylated	Diffuse, Right Frontal, Parietal, Temporal	60	Yes	No	No	No	No	Yes
7	56	M	No	CR	Wild-type	Methylated	Left Temporal	90	Yes	No	No	No	Yes	No
8	61	M	No	PR	Wild-type	Unmethylated	Left Temporal	90	No	Yes	No	No	No	No
9	21	M	Yes	CR	Wild-type	Unmethylated	Left Thalamus and Midbrain	90	No	No	No	No	No	Yes
10	52	M	Yes	PR	Wild-type	Unmethylated	Right Frontal/Insula	70	Yes	No	No	No	No	Yes
11	35	M	Yes	CR	Wild-type	Unmethylated	Left Occipital	70	No	No	No	No	No	Yes
12	63	M	Yes	PR	Mutant	Methylated	Left Frontal-Temporal	80	Yes	No	No	No	No	Yes
13	36	M	Yes	PR	Wild-type	Unmethylated	Right Temporal	70	No	No	No	No	No	Yes
14	33	M	Yes	PR	Wild-type	Unmethylated	Diffuse, Right Frontal, Temporal	70	Yes	No	No	No	No	Yes