Comparison 2. Patch versus no patch: outcomes at end of follow up.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Any stroke: fatal and non‐fatal	7	1332	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.49 [0.27, 0.90]
1.1 Venous patch	3	346	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.42 [0.14, 1.30]
1.2 Synthetic patch	2	400	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.95 [0.59, 6.45]
1.3 Synthetic or venous patch	2	586	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.25 [0.10, 0.62]
2 Stroke‐related death	6	1019	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.27 [0.05, 1.60]
2.1 Venous patch	3	346	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.46 [0.05, 4.52]
2.2 Synthetic patch	1	87	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.3 Synthetic or venous patch	2	586	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.13 [0.01, 2.04]
3 Stroke ipsilateral to endarterectomy site	6	1141	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.32 [0.16, 0.63]
3.1 Venous patch	3	429	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.42 [0.12, 1.47]
3.2 Synthetic patch	1	100	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.53 [0.05, 5.19]
3.3 Synthetic or venous patch	2	612	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.25 [0.10, 0.62]
4 Death from all causes	7	1332	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.78 [0.54, 1.12]
4.1 Venous patch	3	346	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.80 [0.45, 1.42]
4.2 Synthetic patch	2	400	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.90 [0.39, 2.05]
4.3 Synthetic or venous patch	2	586	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.69 [0.38, 1.26]
5 Any stroke or death	6	1019	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.59 [0.42, 0.84]
5.1 Venous patch	3	346	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.69 [0.40, 1.20]
5.2 Synthetic patch	1	87	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.62 [0.23, 1.66]
5.3 Synthetic or venous patch	2	586	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.51 [0.30, 0.86]
6 Restenosis/occlusion of the operated artery	8	1719	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.24 [0.17, 0.34]
6.1 Venous patch	3	429	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.34 [0.17, 0.66]
6.2 Synthetic patch	3	678	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.46 [0.22, 0.98]
6.3 Synthetic or venous patch	2	612	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.15 [0.09, 0.25]