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. 2009 Oct 7;2009(4):CD000160. doi: 10.1002/14651858.CD000160.pub3

Vleeschauwer 1987.

Methods R ‐ sealed envelopes (not opaque or numbered) 
 Clinical and Duplex FU blind 
 Crossovers: none 
 Exclusions during trial: patients with residual stenosis/occlusion (number known) 
 Patients lost to FU: none
Participants Germany 
 126 patients 
 174 operations 
 60% male 
 Mean age: 64 years 
 30% asymptomatic carotid disease 
 Comparability: age, sex, vascular risk factors, % asymptomatic disease not reported by treatment group
Interventions Rx: autologous vein patch 
 Control: primary closure 
 Routine shunting for all 
 Postoperative aspirin (1 g) for all
Outcomes Death < 30 days and end of FU 
 Stroke < 30 days and end of FU 
 Wound haemorrhage, infection 
 Restensosis > 50% or occlusion at end of FU (Duplex)
Notes Ex: Recurrent stenosis, kinked ICA 
 FU: 1 year
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? High risk C ‐ Inadequate

CABG: coronary artery bypass graft 
 DSA: digital subtraction angiography 
 Ex: exclusion criteria 
 FU: follow up 
 GA: general anaesthesia 
 ICA: internal carotid artery 
 R: concealment of allocation 
 RIND: reversible ischaemic neurological deficit 
 Rx: treatment 
 TIA: transient ischaemic attack