Vleeschauwer 1987.
Methods | R ‐ sealed envelopes (not opaque or numbered) Clinical and Duplex FU blind Crossovers: none Exclusions during trial: patients with residual stenosis/occlusion (number known) Patients lost to FU: none | |
Participants | Germany 126 patients 174 operations 60% male Mean age: 64 years 30% asymptomatic carotid disease Comparability: age, sex, vascular risk factors, % asymptomatic disease not reported by treatment group | |
Interventions | Rx: autologous vein patch Control: primary closure Routine shunting for all Postoperative aspirin (1 g) for all | |
Outcomes | Death < 30 days and end of FU Stroke < 30 days and end of FU Wound haemorrhage, infection Restensosis > 50% or occlusion at end of FU (Duplex) | |
Notes | Ex: Recurrent stenosis, kinked ICA FU: 1 year | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | High risk | C ‐ Inadequate |
CABG: coronary artery bypass graft DSA: digital subtraction angiography Ex: exclusion criteria FU: follow up GA: general anaesthesia ICA: internal carotid artery R: concealment of allocation RIND: reversible ischaemic neurological deficit Rx: treatment TIA: transient ischaemic attack