| Methods |
Randomised study |
| Participants |
Males and females 18 to 55 years of age |
| Interventions |
Oral clarithromycin/oral azithromycin or oral levofloxacin/oral high‐dose amoxicillin |
| Outcomes |
Primary: clinical response. Secondary: adverse effects |
| Notes |
Study conducted in Rural Health Training Centre in India |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
No stated method of randomisation |
| Allocation concealment (selection bias) |
Unclear risk |
Not explicitly stated |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Not explicitly stated |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
No CONSORT diagram presented, therefore reasons for exclusion of patients at the entry level are unclear |
| Selective reporting (reporting bias) |
Low risk |
The study reported on every patient that was included in the trial (n = 31) |
| Other bias |
Low risk |
No explicit mention of biopharmaceutical industry involvement |
