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. 2020 Mar 11;11:298. doi: 10.3389/fphar.2020.00298

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Copyright © 2020 Feng, Wan, Zhang, Yu, Shao, He, Wan and Jin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histopathological changes in hippocampus tissues of rats in each group were observed by HE staining. (A) The hippocampus tissues of each group rats at 200-fold magnification after HE staining, and necrotic cells indicated by black tips. (B) The hippocampus tissues of each group rats at 200-fold magnification after HE staining, and necrotic cells indicated by black tips (n = 3). Sham, sham operation group; MCAO, middle cerebral artery occlusion; LY294002, 2-(4-morpholinyl)-8-phenyl-chromone; DHI, Danhong Injection; NMDP, nimodipine.