TABLE 2.
Expression of p53 mRNA in rat brain tissue ( ± s, n = 3).
Group | p53 mRNA expression |
Sham | 1.00 ± 0.11 |
MCAO | 1.98 ± 0.21▲▲ |
DHI | 1.43 ± 0.16* |
LY294002 | 3.15 ± 0.35** |
DHI + LY294002 | 2.55 ± 0.25* |
NMDP + LY294002 | 1.58 ± 0.19## |
Compared with the sham operation group, ▲▲P < 0.01; compared with the MCAO group, *P < 0.05, **P < 0.01; compared with the LY294002 group, ##P < 0.01. I/R, ischemia-reperfusion; MCAO, middle cerebral artery occlusion; LY294002, 2-(4-morpholinyl)-8-phenyl-chromone; DHI, Danhong Injection; NMDP, nimodipine.