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. 2020 Mar 13;12:1913–1927. doi: 10.2147/CMAR.S228718

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© 2020 Wong et al.

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Analysis of the growth inhibition effect of individual CCBs on A549 chemoresistant sublines analyzed by MTT assay. Group-1 compared chemoresistant A549/D16 cells (A) treated with DOC (16 nM) to blank control cells, and group-2 compared cells treated with CCB (5 μM) only with cells treated with CCB (5 μM) combined with DOC (16 nM). Group-3 compared cells treated with CCB (10 μM) with cells treated with CCB (10 μM) and DOC (16 nM). The data were analyzed by MTT assay for three-day periods. Similar conditions for A549/V16 subline were applied and studied (B). *p<0.05 was considered statistically significant.