Table 3.
Precision and Accuracy of Parecoxib and Valdecoxib in Beagle Plasma (n=6, Mean ± SD)
| Compounds | Spiked (ng/mL) |
Intra-Day | Inter-Day | ||
|---|---|---|---|---|---|
| RSD (%) | RE (%) | RSD (%) | RE (%) | ||
| Parecoxib | 10 | 3.65 | −1.38 | 5.91 | −0.33 |
| 800 | 2.81 | −0.57 | 3.85 | 0.45 | |
| 3000 | 1.67 | −0.76 | 2.28 | −0.54 | |
| Valdecoxib | 10 | 3.22 | −0.51 | 4.71 | −0.49 |
| 800 | 2.39 | 1.96 | 3.91 | −0.43 | |
| 3000 | 1.36 | −0.68 | 2.41 | −0.25 | |