Table 2.
IHTAG content and fasting and postprandial biochemical characteristics of participants (n=19) taking omega-3 FA
| Baseline | 8 weeks | |
| IHTAG (%) | 7.8±1.6 | 6.3±1.3* |
| Fasting plasma biochemical parameters | ||
| VLDL-TAG (µmol/L) | 1335±57 | 1069±97* |
| VLDL-ApoB (mg/dL) | 3.5±0.5 | 4.6±0.7 |
| VLDL-TAG/VLDL-ApoB† | 34 791±6600 | 17 657±2945* |
| Postprandial plasma biochemical parameters (AUC, time-averaged) | ||
| Chylomicron-TAG (µmol/L) | 564±70 | 449±52 |
| VLDL-TAG (µmol/L) | 1546±57 | 1330±79* |
| NEFA (µmol/L) | 89±21 | 80±18 |
| 3OHB (µmol/L) | 81.5±11.3 | 87.3±11.6 |
| Postprandial13C-labeled plasma biochemical parameters (AUC, time-averaged) | ||
| 13C plasma TAG-palmitate (µmol/L) | 3.9±0.4 | 3.3±0.3 |
| 13C chylomicron-TAG palmitate (µmol/L) | 2.9±0.3 | 2.0±0.2* |
| 13C NEFA-palmitate (µmol/L) | 0.43±0.04 | 0.45±0.03 |
| 13C VLDL-TAG palmitate (µmol/L) | 0.87±0.07 | 0.79±0.05 |
| Whole-body 13CO2 (µmol/min) | 2.8±0.2 | 3.2±0.2* |
| Hepatic 13CO2 (µmol/min) | 0.91±0.07 | 1.0±0.06* |
| Respiratory exchange ratio | 0.96±0.02 | 0.89±0.01** |
Data expressed as mean±SEM.
*P<0.05, **p<0.01 baseline vs 8 weeks.
†Molar ratio.
AUC, areas under the curve; IHTAG, intrahepatic triacylglycerol; NEFA, nonesterified fatty acids; 3OHB, 3-hydroxybutyrate; TAG, triacylglycerol; VLDL, very low-density lipoprotein.