Table 3. Cumulative Doses of Medications Given During Surgery.
| Medications | Median (Interquartile Range) | Median Difference (95% CI) | P Value | |
|---|---|---|---|---|
| Intervention (n = 31) | Control (n = 29) | |||
| Noradrenaline, μg | 1034.0 (770.7-1720.0) | 925.7 (428.7-2131.0) | −118.0 (−534.3 to 418.0) | .67 |
| Noradrenaline, μg/kg/mina | 0.057 (0.033-0.071) | 0.040 (0.021-0.066) | −0.010 (−0.025 to 0.005) | .18 |
| Ephedrine, mg | 10.0 (0.0-22.5) | 10.0 (10.0-16.3) | 0.0 (−5.0 to 5.0) | .52 |
| Phenylephrine, μg | 200.0 (100.0-600.0) | 300.0 (100.0-500.0) | 0.0 (−200.0 to 100.0) | .84 |
| Fluids, mL | 2100.0 (1750.0-3000.0) | 1800.0 (1550.0-2950.0) | −150 (−600.0 to 470.0) | .58 |
| Colloids, mL | 250.0 (0.0-500.0) | 0.0 (0.0-500.0) | 0.0 (−250.0 to 0.0) | .09 |
| Crystalloids, mL | 1800.0 (1500.0-2700.0) | 1800.0 (1450.0-2650.0) | 100.0 (−550.0 to 300.0) | .72 |
| Fluid balance, mLb | 1180.0 (680.0-1650.0) | 1150.0 (582.5-1552.5) | −80.00 (−480.00 to 300.00) | .62 |
| Propofol, mgc | 100 (60-1647) | 125 (50-2568) | 20 (−1430 to 1467) | .90 |
| Sevoflurane, % volume | 1.67 (1.48-1.73) | 1.57 (1.42-1.75) | −0.02 (−0.80 to 0.17) | .66 |
| Sufentanil (intravenous), μg | 80.0 (50.0-85.0) | 70.0 (53.8-85.0) | −5.0 (−25.0 to 15.0) | .51 |
| Morphine, mgd | 10.00 (8.50-11.25) | 10.00 (8.75-15.00) | 0.00 (−2.50 to 6.00) | .83 |
| Epidural analgesia, No. (%) of patients | 21 (68) | 13 (45) | .07 | |
a
Noradrenaline dose corrected for patient body weight.
b
Fluid balance at the end of surgery.
c
Calculated for patients who received propofol (n = 7 in the intervention group and n = 12 in the control group).
d
Calculated for patients who received morphine (n = 6 in the intervention group and n = 13 in the control group).