Figure 1. A: The experimental scheme for quantitative tissue-based proteomic profiling of prostate cancer (PCa) tissues. B: Overview of the frequency of differentially expressed proteins from prostate tissues identified using a proteomics approach. C: Venn diagrams depicting the up-regulated (left) and down-regulated proteins (right) among the patient’s with different T-stage (T2 as PCa, or T3 as advanced PCa) and serum prostate-specific antigen level (LP: low level; HP: high level). Ctrl: Control; DEPs: differentially expressed proteins.