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. 2020 Mar 17;8(1):e000316. doi: 10.1136/jitc-2019-000316

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Numbers of circulating lymphocytes during treatment. (A) The number of IFN-γ-producing cells after αGalCer restimulation was assessed by ELISPOT assay. The linear mixed effect model for repeated measurements was used to estimate the geometric mean, SE, and 95% CI of the mean of each measuring point of immune monitoring, which can address all available post-baseline data; ***p<0.001. (B) A comparison of overall survival of good responders with increased IFN-γ-producing cells (n=24) and poor responders (n=8). ELISPOT, enzyme-linked immunospot; IFN-γ, interferon-γ.