Table 2.

Comparison of the different microbeam detection methods evaluated in this work.

	Microbeam detection method
	vM1212 detector	Zeiss Axio Imager 2 (+ EBT3 film)	Epson Expression 10000XL (+ EBT3 film)
Advantages	Real time measurement and analysis Short exposure is sufficient to obtain accurate profile information	Highest spatial resolution No dose rate dependence49	Lower cost Established clinical workflow No dose rate dependence49
Disadvantages	Limited life expectancy due to cumulative radiation damage Spatial resolution limited by 50 µm pixel pitch	24 hours self‐development Complex and time consuming analysis process	24 hours self‐development Poorest spatial resolution ad hence limited suitability for microbeam applications
	Higher price	Necessity to establish procedures and workflow for wider uptake of this method	Software licensing costs