Table 6a.
Univariate and multivariate analyses of clinicopathologic findings and CNA pattern (3p24.3‐mixed) as predictors of metachronous metastasis in clear cell renal cell carcinoma of the first cohort
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Variables | HR | 95% CI | P | HR | 95% CI | P |
| Size, mm | ||||||
| >40 vs ≤40 | 5.125 | 1.316‐33.675 | .0166* | 3.443 | 0.841‐23.279 | .0890 |
| Fuhrman grade | ||||||
| 3 vs 2 | 3.421 | 0.981‐11.422 | .0534 | |||
| Necrosis | ||||||
| Present vs absent | 2.132 | 0.465‐7.420 | .2959 | |||
| Venous invasion | ||||||
| Positive vs negative | 1.332 | 0.072‐7.081 | .7860 | |||
| pT stage | .5353 | |||||
| pT2 vs pT1 | 1.901 | 0.278‐8.087 | .4580 | |||
| pT3 vs pT1 | 2.282 | 0.338‐9.541 | .3450 | |||
| pT3 vs pT2 | 1.200 | 0.143‐10.104 | .8564 | |||
| CNA pattern (3p24.3‐mixed) | ||||||
| Negative vs positive | 6.241 | 1.576‐41.394 | .0075* | 4.432 | 1.079‐30.147 | .0379* |
Abbreviations: CI, confidence interval; CNA, copy number alteration; HR, hazard ratio.
*
P < .05.