Table 3.

P‐values for the Wilcoxon signed‐rank test between Elastix and each of the three network variants.

Metric	Overlap loss	Deformation loss	Hybrid loss
Dice coefficient	$P<{10}^{-5}\star$	P > 0.99†	$P<{10}^{-5}\star$
95th perc. Hausdorff	$P<{10}^{-3}\star$	P > 0.99†	$P<{10}^{-3}\star$
Prostate centroid	P > 0.11∘	P > 0.99†	P < 0.05∘

Significant improvements (P < 0.01) over Elastix are indicated with ⋆, no significant differences with ^∘, and cases where Elastix is superior with †.