Figure 3.

Proteomic analysis of conditional PSD95 TAP‐tagged mice reveals differentially interacting proteins in specific brain subregions. (a) Lysates from the conditionally TAP‐tagged mice were probed for FLAG to confirm expression of the tag. Expression was detected in PSD95^cTAP/+;Grik4‐Cre lines (PSD95^cTAP/+/Cre). The lysates were taken from the hippocampi of the Grik4‐Cre mice. No leaky expression of the tag could be detected in the cortex (Cx), hippocampus (Hp) or striatum (Str) of the PSD95^cTAP/+ mice. PSD95^TAP/+ mice were used as a positive control, and the tag was detected in all tested brain regions. (b) PSD95 expression was detected in all samples