Table 3.

Breast cancer excess mortality hazard by stage, country HDI and age at diagnosis

		Univariable analysis			Multivariable adjusted1 model
Prognostic factors	Number of cases	Hazard ratio	95% CI	p value	Hazard ratio	95% CI	p value
Age at diagnosis (years)
<45	790	1 (Ref)			1 (Ref)
45–54	615	1.0	0.8–1.2	0.83	1.0	0.8–1.2	0.1
55–64	477	1.1	0.9–1.3	0.61	1.2	0.9–1.4	0.2
65–74	244	0.9	0.7–1.3	0.70	1.1	0.8–1.5	0.33
75+	179	0.9	0.6–1.4	0.70	0.9	0.6–1.5	0.57
Country‐level HDI
High HDI	596	1 (Ref)			1 (Ref)
Medium HDI	596	2.3	1.4–3.8	0.001	1.9	1.2–3.1	0.01
Low HDI	1,119	2.8	1.7–4.5	<0.001	2.3	1.4–3.7	0.001
Stage at diagnosis
Early stage	301	1 (Ref)			1 (Ref)
Late stage	555	2.7	2.0–3.6	<0.001	2.5	1.8–3.3	<0.001
Unknown stage	962	2.2	1.6–2.9	<0.001	1.9	1.4–2.5	<0.001

¹Adjusted for stage at diagnosis, country‐level human development index (HDI) and age at diagnosis.

Abbreviation: 95% CI, 95% confidence interval.