Table 4.
HRs (95% CI) of risk of death from all causes according to standardised scores for attitudes to ageing at age 72 years, adjusted for brain-PAD and covariates (n=622)
| Adjustments | Attitudes to ageing scales (per SD) | |||||
| Physical change | †p/pFDR | Psychosocial loss | †p/pFDR | Psychological growth | †p/pFDR | |
| Age and sex | 0.64 (0.53 to 0.77) | <0.001/0.003 | 1.44 (1.21 to 1.70) | <0.001/0.003 | 0.88 (0.73 to 1.06) | 0.169/0.195 |
| Age, sex and brain-PAD | 0.65 (0.54 to 0.78) | <0.001/0.003 | 1.42 (1.20 to 1.69) | <0.001/0.003 | 0.89 (0.74 to 1.07) | 0.217/0.235 |
| Age, sex and education | 0.65 (0.54 to 0.79) | <0.001/0.003 | 1.41 (1.18 to 1.67) | <0.001/0.003 | 0.84 (0.70 to 1.02) | 0.076/0.106 |
| As above plus brain-PAD | 0.67 (0.56 to 0.81) | <0.001/0.003 | 1.39 (1.17 to 1.66) | <0.001/0.003 | 0.84 (0.70 to 1.02) | 0.085/0.116 |
| Age, sex, smoking and alcohol | 0.66 (0.55 to 0.80) | <0.001/0.003 | 1.36 (1.15 to 1.61) | <0.001/0.003 | 0.88 (0.73 to 1.06) | 0.165/0.194 |
| Age, sex, smoking and alcohol plus brain-PAD | 0.68 (0.56 to 0.81) | <0.001/0.003 | 1.35 (1.14 to 1.60) | 0.001/0.002 | 0.89 (0.74 to 1.06) | 0.194/0.133 |
| Age, sex, chronic disease and walking speed | 0.69 (0.57 to 0.84) | <0.001/0.003 | 1.34 (1.12 to 1.60) | 0.001/0.002 | 0.87 (0.73 to 1.05) | 0.140/0.168 |
| Age, sex, chronic disease and walking speed plus brain-PAD | 0.71 (0.58 to 0.86) | <0.001/0.003 | 1.34 (1.12 to 1.60) | 0.001/0.002 | 0.88 (0.73 to 1.06) | 0.180/0.204 |
| Age, sex, anxiety and depression | 0.68 (0.56 to 0.82) | <0.001/0.003 | 1.36 (1.11 to 1.67) | 0.003/0.006 | 0.93 (0.77 to 1.13) | 0.477/0.492 |
| Age, sex, anxiety and depression plus brain-PAD | 0.68 (0.56 to 0.82) | <0.001/0.003 | 1.37 (1.12 to 1.67) | 0.002/0.004 | 0.94 (0.78 to 1.13) | 0.489/0.497 |
| All* | 0.76 (0.62 to 0.92) | 0.006/0.011 | 1.27 (1.04 to 1.55) | 0.020/0.033 | 0.88 (0.73 to 1.07) | 0.196/0.216 |
*Age, sex, brain-PAD, educational attainment, total number of chronic diseases, time taken to walk 6 metres, smoking status, frequency of alcohol consumption, HADS anxiety score, HADS depression score.
†pFDR is the p value corrected for multiple comparisons using the False Discovery Rate.
Brain-PAD, brain-predicted age difference; HADS, Hospital Anxiety and Depression Scale.