Figure 7.

Effects of TRAP1 on diabetes-induced apoptosis and mitochondrial damage in rat kidney. (a) Representative images of (TUNEL) staining (red: TUNEL; blue: DAPI); scale bar, 100 μm. (b) Quantification of TUNEL-positive cells in fields. (c) Mitochondria of tubular epithelial cells viewed by TEM; scale bar, 1 μm. (d) ATP levels measured by firefly luciferase detection. (e, f) Representative photomicrographs and quantification of ROS staining in rat renal tubules; scale bar, 100 μm. The results are presented as the mean ± SEM; n = 4‐6, ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001 for each pair of groups indicated.