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Classical-cadherin-mediated adhesions mechanically connect cells in tissues A) Schematic depicting homophilic cadherin adhesion between two cells and their cytoskeleton. Cadherin-mediated mechanotransduction drives many biological-signaling events. Schematic of cytoskeletal organizaton and its coupling with cadherin-mediated adhesions in B) cardiac muscle and C) epithelial layer of the skin.
