Table 2.
Patient characteristics
| Covariate | Control | Other MPS | Morquio A |
|---|---|---|---|
| (n = 560) | (n = 33) | (n = 13) | |
| Male | 301 (53.8%) | 22 (67%) | 8 (61%) |
| Female | 259 (46.2%) | 11 (33%) | 5 (39%) |
| Age at visit (years) | 13.14 (4.01) | 12.41 (4.74) | 13.98 (10.0) |
| SBP (mm Hg) | 106 (10.42) | 107 (10.79) | 103 (12.8) |
| DBP (mm Hg) | 58.00 (7.78) | 55.21 (13.54) | 70.6 (12.2) |
| Pulse Pressure (mm Hg) | 48.12 (9.49) | 51.97 (11.81) | 31.92 (6.53) |
| Height (cm) | 155 (18.30) | 132 (16.55) | 108 (21.89) |
| cIMT (mm) | 0.44 (0.04) | 0.56 (0.06) | 0.56 (0.03) |
| cCSD (%) | 32.03 (8.35) | 28.16 (15.74) | 25.37 (8.81) |
| cCSC1 (mm2 · mm Hg−1) | 0.16 (0.05) | 0.14 (0.08) | 0.22 (0.07) |
| cIEM (mm Hg) | 951 (379.84) | 1355 (811.82) | 772 (371) |
Values presented are mean (sd) or n (%) where indicated. The “Other MPS” cohort is composed of 17 MPS I, 9 MPS II, 4 MPS IIIA, and 3 MPS VI patients. The Morquio A data includes one patient (#2), who underwent two carotid ultrasounds 16 months apart
SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, cIMT Carotid Intima-Media Thickness, cCSD Carotid Cross-sectional Distensibility, cCSC1 Carotid Cross-sectional Compliance, cIEM Carotid Incremental Elastic Modulus