Table 3.
Ratio comparisons between mean carotid measures of Morquio A patients, non-Morquio MPS patients (“Other MPS”), and pediatric control groups adjusted for sex, age, and height
| Vascular Measure | Covariate | Ratio (95% CI) | P-value |
|---|---|---|---|
| Control vs. Morquio A | 0.80 (0.76, 0.84) | < 0.001 | |
| Other MPS vs. Morquio A | 1.00 (0.95, 1.05) | 0.956 | |
| cIMT (mm) | Female (vs. Male) | 0.98 (0.97, 1.00) | 0.038 |
| Age (per 10 yr) | 1.03 (0.99, 1.06) | 0.114 | |
| Height (per 10 cm) | 1.00 (0.99, 1.01) | 0.931 | |
| Control vs. Morquio A | 1.07 (0.88, 1.30) | 0.521 | |
| Other MPS vs. Morquio A | 1.02 (0.80, 1.30) | 0.875 | |
| cCSD (%) | Female (vs. Male) | 1.01 (0.97, 1.05) | 0.668 |
| Age (per 10 yr) | 0.71 (0.64, 0.79) | < 0.001 | |
| Height (per 10 cm) | 1.04 (1.02, 1.06) | < 0.001 | |
| Control vs. Morquio A | 0.70 (0.57, 0.87) | < 0.001 | |
| cCSC1 | Other MPS vs. Morquio A | 0.61 (0.47, 0.79) | < 0.001 |
| (mm2 · mm Hg−1) | Female (vs. Male) | 0.95 (0.90, 1.00) | 0.045 |
| Age (per 10 yr) | 0.83 (0.74, 0.93) | 0.001 | |
| Height (per 10 cm) | 1.01 (0.98, 1.04) | 0.502 | |
| Control vs. Morquio A | 1.50 (1.15, 1.96) | 0.003 | |
| Other MPS vs. Morquio A | 2.18 (1.63, 2.92) | < 0.001 | |
| cIEM (mm Hg) | Female (vs. Male) | 0.95 (0.90, 1.01) | 0.121 |
| Age (per 10 yr) | 1.48 (1.30, 1.70) | < 0.001 | |
| Height (per 10 cm) | 0.99 (0.95, 1.02) | 0.364 |
Ratios less than 1.00 indicate the first comparator is less than the second comparator; ratios greater than 1.00 indicate the first comparator is greater than the second comparator. Significant comparisons are highlighted in bold