Table 4.
Comparisons between mean carotid measures of Morquio A patients treated with Enzyme Replacement Therapy (ERT) and those not treated with ERT
| Score | Covariate | Difference (95% CI) | P-value |
|---|---|---|---|
| cIMT | ERT (vs. not) | 0.00 (−0.03, 0.03) | 0.916 |
| (mm) | Female (vs. Male) | −0.01 (−0.05, 0.02) | 0.402 |
| Age (per 10 yr) | 0.01 (− 0.01, 0.02) | 0.587 | |
| Height (per 10 cm) | 0.00 (−0.01, 0.00) | 0.408 | |
| cCSD | ERT (vs. not) | −2.20 (−8.91, 4.51) | 0.520 |
| (%) | Female (vs. Male) | 0.14 (−8.06, 8.34) | 0.973 |
| Age (per 10 yr) | 1.31 (−4.23, 6.86) | 0.643 | |
| Height (per 10 cm) | −2.98 (−5.38, −0.58) | 0.015 | |
| cCSC1 | ERT (vs. not) | −0.03 (− 0.08, 0.02) | 0.279 |
| (mm2 | Female (vs. Male) | −0.03 (− 0.09, 0.04) | 0.465 |
| · mm Hg−1) | Age (per 10 yr) | 0.01 (−0.03, 0.05) | 0.686 |
| Height (per 10 cm) | −0.02 (− 0.04, − 0.01) | 0.005 | |
| cIEM | ERT (vs. not) | 136.86 (2.44, 271.29) | 0.046 |
| (mm Hg) | Female (vs. Male) | 14.88 (− 145.24, 175.00) | 0.855 |
| Age (per 10 yr) | 34.26 (− 105.85, 174.38) | 0.632 | |
| Height (per 10 cm) | 130.82 (80.41, 181.23) | < 0.001 |
Analyses are adjusted for sex, age, and height. Significant comparisons are highlighted in bold. Height is a significant influence upon cCSD, cCSC1, and cIEM