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. 2020 Mar 17;25:21. doi: 10.1186/s11658-020-00215-y

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — Expression and relationship of CASC2, miR-222 and ING5 in serum samples of PAH patients. a-c CASC2, miR-222 and ING5 expression levels were measured in the serum samples of PAH patients and were compared to the expression in healthy controls. d-e Correlation between CASC2 and miR-222 expression, miR-222 and ING5 expression, or ING5 and CASC2 expression in serum samples of PAH patients was analyzed using Spearman’s correlation test. Results are presented as the average of three independent replicates. ***P < 0.001