Table 2.

The results of simplified CDAI, PDAI, IBDQ, Wexner, and VAS scores

	Observation group (n = 11)	Control group (n = 11)	Treatment difference (95%CI)	pvalue
Simplified CDAI
Baseline	4.3 ± 0.5	4.4 ± 0.7
Month 3	2.1 ± 0.3	4.9 ± 0.7
Change from baseline	2.2 ± 0.6	0.5 ± 0.7	1.6 (1.1 to 2.2)	0.000
Month 6	2.5 ± 1.0	4.6 ± 0.7
Change from baseline	1.7 ± 1.2	0.5 ± 0.7	1.3 (0.4 to 2.1)	0.006
Month 12	2.7 ± 1.5	4.7 ± 0.6
Change from baseline	1.7 ± 1.4	0.5 ± 0.5	1.2 (0.2 to 2.2)	0.023
PDAI
Baseline	8.5 ± 1.4	9.5 ± 1.7
Month 3	1.3 ± 1.1	3.5 ± 0.8
Change from baseline	7.3 ± 2.0	6.0 ± 1.3	1.3 (− 0.2 to 0.8)	0.090
Month 6	1.7 ± 1.6	3.5 ± 1.5
Change from baseline	6.8 ± 1.8	6.1 ± 1.9	0.7 (− 0.9 to 2.3)	0.361
Month 12	1.9 ± 2.4	3.1 ± 2.1
Change from baseline	6.6 ± 2.2	6.5 ± 2.5	0.2 (− 1.9 to 2.3)	0.858
IBDQ
Baseline	143.5 ± 19.8	137.9 ± 29.7
Month 3	202.1 ± 19.9	179.5 ± 28.0
Change from baseline	58.6 ± 7.1	41.5 ± 36.6	17.1 (− 7.7 to 41.9)	0.158
Month 6	193.2 ± 31.5	174.1 ± 19.8
Change from baseline	49.7 ± 16.1	36.5 ± 32.1	13.2 (− 9.4 to 35.8)	0.238
Month 12	187.8 ± 33.5	166.1 ± 23.4
Change from baseline	44.4 ± 17.6	29.1 ± 34.6	15.3 (− 9.2 to 39.7)	0.207
Wexner score
Baseline	1.2 ± 1.3	1.5 ± 0.7
Month 3	0.8 ± 1.3	1.4 ± 0.7
Change from baseline	0.4 ± 0.5	0.2 ± 0.4	0.1 (− 0.2 to 0.6)	0.362
Month 6	0.6 ± 1.0	1.2 ± 0.8
Change from baseline	0.5 ± 0.7	0.7 ± 0.6	0.2 (− 0.8 to 0.4)	0.530
Month 12	0.5 ± 0.8	1.2 ± 0.8
Change from baseline	0.6 ± 0.7	0.7 ± 0.6	0.1 (− 0.7 to 0.5)	0.750
VAS
Baseline	0.8 ± 1.0	1.1 ± 1.0
Day 1	1.5 ± 1.5	4.9 ± 0.8
Change from baseline	0.9 ± 1.1	3.8 ± 1.0	2.9 (2.0 to 3.9)	0.000
Day 3	1.1 ± 1.0	4.3 ± 0.8
Change from baseline	0.5 ± 0.9	3.2 ± 1.3	2.7 (1.7 to 3.7)	0.000
Day7	0.6 ± 0.5	3.2 ± 0.8
Change from baseline	0.4 ± 0.7	2.1 ± 1.3	1.7 (0.8 to 2.6)	0.001
Day 15	0.4 ± 0.5	2.3 ± 0.6
Change from baseline	0.6 ± 0.9	1.4 ± 1.1	0.7 (0.2 to 1.6)	0.112