Fig. 1.

MiR-206 expression is downregulated in NSCLC tissues and cell lines. a The miR-206 mRNA level in NSCLC tissues and the corresponding normal mucosa tissues detected by q-RT-PCR assay. Quantitative data are presented as the mean ± SEM, n = 50. ***P < 0.001 compared with the normal tissues. b Kaplan–Meier curves for overall survival analysis based on miR-206 expression. c miR-206 expression in human lung epithelia BEA-2B cells and human lung cell lines, including A549, NCI-H365, NCI-H460, SPCA-1 and XL-1, detected with q-RT-PCR assay. Quantitative data are presented as mean ± SEM, n = 50. ***P < 0.001 compared with BEA-2B cells