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. 2015 Jan 25;2015(1):CD010653. doi: 10.1002/14651858.CD010653.pub2
Study Reason for exclusion
Abrams 1973 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Abrams 1981 Data insufficient to construct appropriate 2 x 2 table.
Ahmed 1984 Participants did not present with psychotic symptoms.
Data insufficient to construct appropriate 2 x 2 table.
Al‐Ansari 1989 All participants had a diagnosis of schizophrenia.
Anselmetti 2007 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Asnis 1982 All participants had a diagnosis of schizophrenia.
Basu 1999 Assessors not blinded to diagnosis in a retrospective study.
Beckmann 1990 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Berner 1984 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
FRS not routinely performed on patients in study.
Berner 1986 FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Berner 1986a Data insufficient to construct appropriate 2 x 2 table.
Bland 1978 All participants had a diagnosis of schizophrenia.
Bland 1979 Participants did not present with psychotic symptoms.
All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Botros 2006 All participants had a diagnosis of schizophrenia.
Burbach 1984 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Cardno 2002 Data insufficient to construct appropriate 2 x 2 table.
Ceccherini‐Nelli 2003 All participants had a diagnosis of schizophrenia.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Assessors not blinded to diagnosis in a retrospective study.
Cernovsky 1985 All participants had a diagnosis of schizophrenia.
Chandrasena 1979 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Coffey 1993 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Assessors not blinded to diagnosis in a retrospective study.
Compton 2008 Data insufficient to construct appropriate 2 x 2 table.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Conus 2004 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Cowell 1996 All participants had a diagnosis of schizophrenia.
Craddock 1996 Data insufficient to construct appropriate 2 x 2 table.
FRS not routinely performed on patients in study.
Cuesta 2007 Participants did not present with psychotic symptoms.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Deister 1993 All participants had a diagnosis of schizophrenia.
Deister 1994 Participants did not present with psychotic symptoms.
All participants had a diagnosis of schizophrenia.
FRS not routinely performed on patients in study.
Dollfus 1992 Data insufficient to construct appropriate 2 x 2 table.
Dollfus 1993 All participants had a diagnosis of schizophrenia.
Dollfus 1993a Participants did not present with psychotic symptoms.
Data insufficient to construct appropriate 2 x 2 table.
FRS not routinely performed on patients in study.
Endicott 1982 Data insufficient to construct appropriate 2 x 2 table.
FRS not routinely performed on patients in study.
Endicott 1986 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Eva 1984 All participants had a diagnosis of schizophrenia.
Evans 1981 All participants had a diagnosis of schizophrenia.
Fanous 2012 All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Fourneret 2001 Participants did not present with psychotic symptoms.
All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Franck 2002 All participants had a diagnosis of schizophrenia.
Ganesan 2005 Participants did not present with psychotic symptoms.
All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Gharagozlou 1979 Participants did not present with psychotic symptoms.
Gift 1980 Participants did not present with psychotic symptoms.
Data insufficient to construct appropriate 2 x 2 table.
FRS not routinely performed on patients in study.
Glazer 1987 Participants did not present with psychotic symptoms.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Gur 1994 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Gureje 1987 All participants had a diagnosis of schizophrenia.
Hayashi 1998 Participants did not present with psychotic symptoms.
All participants had a diagnosis of schizophrenia.
FRS not routinely performed on patients in study.
Helmes 1983 Participants did not present with psychotic symptoms.
Data insufficient to construct appropriate 2 x 2 table.
Hill 1996 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Idrees 2010 All participants had a diagnosis of schizophrenia.
Jakobsen 2006 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
FRS not routinely performed on patients in study.
Kendell 1979 Participants did not present with psychotic symptoms.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Klosterkotter 1992 All participants had a diagnosis of schizophrenia.
Koehler 1976 All participants had a diagnosis of schizophrenia.
Koehler 1978 FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Kulhara 1988 All participants had a diagnosis of schizophrenia.
Kulhara 1989 All participants had a diagnosis of schizophrenia.
Landmark 1986 Participants did not present with psychotic symptoms.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Landmark 1990 All participants had a diagnosis of schizophrenia.
Lenz 1986 Data insufficient to construct appropriate 2 x 2 table.
Lewine 1982 All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Lewine 1984 Participants did not present with psychotic symptoms.
Data insufficient to construct appropriate 2 x 2 table.
Littlewood 1981 Participants did not present with psychotic symptoms.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Loftus 2000 All participants had a diagnosis of schizophrenia.
Maier 1986 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Makanjuola 1987 All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Malik 1990 All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Marneros 1984 Participants did not present with psychotic symptoms.
No index tests for comparison.
Data insufficient to construct appropriate 2 x 2 table.
Mason 1997 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Matsuura 2004 Participants did not present with psychotic symptoms.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Mauri 1992 Data insufficient to construct appropriate 2 x 2 table.
FRS not routinely performed on patients in study.
McGuffin 1984 Data insufficient to construct appropriate 2 x 2 table.
McGuffin 1991 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Melges 1977 Participants did not present with psychotic symptoms.
Data insufficient to construct appropriate 2 x 2 table.
Mellor 1970 All participants had a diagnosis of schizophrenia.
Menezes 1993 Data insufficient to construct appropriate 2 x 2 table.
Modestin 2003 All participants had a diagnosis of schizophrenia.
Munk‐Jorgensen 1989 All participants had a diagnosis of schizophrenia.
The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
FRS not routinely performed on patients in study.
Data insufficient to construct appropriate 2 x 2 table.
Nakaya 2002 All participants had a diagnosis of schizophrenia.
Ndetei 1984 Data insufficient to construct appropriate 2 x 2 table.
Nordgaard 2008 Participants did not present with psychotic symptoms.
Pela 1982 Data insufficient to construct appropriate 2 x 2 table.
Peralta 1992 Participants did not present with psychotic symptoms.
Data insufficient to construct appropriate 2 x 2 table
Philipp 1986 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Philipp 1986a The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Pihlajamaa 2008 All participants had a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Ross 1991 Participants did not present with psychotic symptoms.
Salvatore 2011 Participants did not present with psychotic symptoms.
FRS not routinely performed on patients in study.
Schanda 1984 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Schiopu 2005 All participants had a diagnosis of schizophrenia.
Serban 1979 All participants had a diagnosis of schizophrenia.
Silverstein 1978 All participants had a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Silverstein 1981 Data insufficient to construct appropriate 2 x 2 table.
Sougey 1987 All participants had a diagnosis of schizophrenia.
Taylor 1972 All participants had a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Thorup 2007 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
Vazquez‐Barquero 1995 The reference standard was not used to separate those with a diagnosis of schizophrenia from the ones without a diagnosis of schizophrenia.
Vega 2006 Participants did not present with psychotic symptoms.
Wciorka 1995 Data insufficient to construct appropriate 2 x 2 table.
Wetterberg 1991 Participants did not present with psychotic symptoms.
FRS not routinely performed on patients in study.
No index tests for comparison.
Data insufficient to construct appropriate 2 x 2 table.
Young 1982 All participants had a diagnosis of schizophrenia.
Data insufficient to construct appropriate 2 x 2 table.
FRS not routinely performed on patients in study.
Zarrouk 1978 All participants had a diagnosis of schizophrenia.

FRS: First Rank Symptoms