Table 1.

Demographical and cerebrospinal fluid (CSF) biomarker values in the Montpellier (AD and NAD) and the WUSTL (amyloid (−) and (+)) cohorts. Results are expressed as means ± standard deviations (SDs). Abbreviations: MMSE Mini-Mental State Examination, AD Alzheimer’s disease, NAD non-Alzheimer’s disease; P significance level of the Student’s t test

Montpellier cohort	NAD	n = 40	AD	n = 10
Variable	Mean	SD	Mean	SD	P
Age (years)	69.3	12.1	75.7	10.1	0.1330
Sex (% male)	67.5%	–	20.0%	–	0.0070*
MMSE	21.2	6.2	18.5	4.4	0.2112
E_Tau (pg/mL)	260	182	715	304	< 0.0001
E_pT181 (pg/mL)	42.9	24.6	95.8	25.0	< 0.0001
MS_pT181 (fmol/mL)	23.8	13.2	60.2	27.7	< 0.0001
MS_pT217 (fmol/mL)	0.948	1.066	11.740	5.006	< 0.0001
WUSTL cohort	Amyloid (−)	n = 51	Amyloid (+)	n = 33
Variable	Mean	SD	Mean	SD	P
Age (years)	62.7	14.3	67.0	16.3	0.2063
Sex (% male)	39.2%	–	57.6%	–	0.1007*
CDR-SB	0.34	1.09	1.77	1.82	0.0004
%E4	17.7%	–	66.7%	–	< 0.0001*
PiB-PET	0.046	0.047	0.670	0.293	< 0.0001
E_pT181 (pg/mL)	47.5	21.5	76.0	25.4	< 0.0001
MS_pT181 (ng/mL)	0.350	0.256	0.596	0.312	< 0.0001
MS_pT217 (ng/mL)	0.057	0.1121	0.202	0.126	< 0.0001

*Chi-squared test for the comparison of two proportions