Table 4.

Optimization of each tenocyte lineage-related factor from T-MSCs and BM-MSCs using response surface methodology

	Estimated value from T-MSCs				Estimated value from BM-MSCs
	Time (day)	p value	Concentration	p value	Time (day)	p value	Concentration	p value
Scleraxis	2.3	0.040	8.4	0.014	2.1	0.014	3.6	0.133
Tenomodulin	2.5	0.011	31.2	0.528	2.9	0.872	0.6	0.034
Decorin	4.8	0.891	1.1	< 0.001	0.6	0.599	2.0	0.004
Collagen I/III	2.8	0.376	7.8	< 0.001	2.1	0.009	2.3	0.018
Tenacin C	2.2	0.038	7.6	0.075	1.9	0.019	0.2	0.805

TGF-β3 transforming growth factor-beta 3, T-MSCs tonsil-derived mesenchymal stem cells, BM-MSCs bone marrow-derived mesenchymal stem cells