Table 4.
Age- and multivariable-adjusted hazard ratios for all-cause mortality according to migraine frequency (N = 27,844)
| Migraine or headache status: | No migraine (N = 18,691) | Non-migraine headache (N = 4025) | Past history of migraine (N = 1518) | Active Migraine < 1/month (N = 2727) | Active migraine at least monthly (N = 703) | Active migraine weekly or daily (N = 180) |
|---|---|---|---|---|---|---|
| HR -ref- | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| All-cause death,N | 3614 | 641 | 306 | 356 | 73 | 22 |
| Age-adjusteda | 1 (ref) | 1.04 (0.96–1.13) | 1.02 (0.91–1.15) | 0.91 (0.82–1.02) | 0.85 (0.68–1.08) | 0.87 (0.58–1.33) |
| Multivariable-adjustedb | 1 (ref) | 1.01 (0.93–1.10) | 1.00 (0.89–1.12) | 0.94 (0.84–1.05) | 0.94 (0.74–1.19) | 0.92 (0.61–1.40) |
Abbreviations: HR Hazard ratio, CI Confidence interval, ref., reference category
a,Adjusted for age at baseline
bAdjusted for the following variables measured at baseline: age, BMI, total cholesterol, smoking, alcohol use, physical activity, diabetes, hypertension, family history of myocardial infarction, and family history of cancer