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. 2020 Mar 18;20:228. doi: 10.1186/s12879-020-04952-5

Table 3.

Univariable and multivariable analysis of factors associated with ICU admissiona in patients with VRE bloodstream infection

ICU admission (n = 13) No ICU admission
(n = 80)
Univariable odds ratio 95% CI p-value Multivariable odds ratio 95% CI p-value
Age, median (IQR), years 47 (40–63) 58 (43–66) 0.98 0.94–1.01 0.212
Male 6 (46%) 43 (54%) 0.74 0.23–2.39 0.612
CDS-VRE, median (IQR) 1.9 (1.5–3.6) 1.9 (1.8–3.4) 1.02 0.67–1.55 0.932
Hematological malignancy 12 (92%) 69 (86%) 1.91 0.23–16.21 0.552
AlloBMT 6 (46%) 18 (23%) 2.95 0.88–9.90 0.080 0.96 0.16–5.96 0.968
Antibiotic days prior to BSI, median (IQR) 20 (18–29) 16 (9–26) 1.03 0.99–1.08 0.163 1.02 0.97–1.08 0.399
ICU admissionb 4 (31%) 25 (31%) 0.98 0.28–3.48 0.972
Hypoalbuminemia daysb, median (IQR) 18 (14–30) 17 (9–29) 1.03 0.97–1.09 0.380
Mucositis grade, median (IQR) 3 (0–4) 0 (0–2) 1.60 1.11–2.30 0.011 1.81 1.04–3.14 0.036
Polymicrobial BSI 3 (23%) 18 (23%) 1.03 0.26–4.16 0.963
Neutropenia at time of BSI 9 (69%) 66 (83%) 0.48 0.13–1.77 0.269
Teicoplanin monotherapy 4 (31%) 55 (69%) 0.23 0.06–0.83 0.024 0.14 0.03–0.66 0.013

CDS-VRE score Chronic Disease Score specific to VRE, CKD chronic kidney disease, AML Acute myeloid leukemia, alloBMT allogeneic bone marrow transplant

aICU admission within 48-h of bloodstream infection

bIn 30 days prior to bloodstream infection