Table 1.

Lugano classification for mantle cell lymphoma staging

Stage	Area of involvement
I	One lymph node region
IE	One extra-nodal site
II	Two or more lymph node regions
IIE	Localized extra-nodal sites on the same side of the diaphragm
III	Lymph node regions or lymphoid structures (e.g., thymus and Waldeyer’s ring) on both sides of the diaphragm
IV	Diffuse or disseminated extra-lymphatic organ involvement