Table 2.
Trajectory of key variables in the overall sample
| Variables | Baseline | Month 3 | Month 6 | Month 9 | Month 12 | p-value |
|---|---|---|---|---|---|---|
| Creatinine | 41.7 (3.7) | 41.5 (3.9) | 47.7 (4.1) | 52.1 (4.5) | 59.1 (5.0) | 0.0001 |
| eGFR | 27.0 (2.3) | 30.3 (2.4) | 27.7 (2.5) | 27.0 (2.8) | 21.5 (3.1) | 0.003 |
| Urea | 1.00 (0.08) | 0.97 (0.08) | 1.04 (0.09) | 1.01 (0.10) | 1.21 (0.11) | 0.178 |
| SBP | 154.4 (3.2) | 142.1 (3.7) | 147.3 (3.9) | 145.5 (4.4) | 156.0 (5.1) | < 0.0001 |
| DBP | 92.4 (2.0) | 85.4 (2.3) | 86.3 (2.4) | 83.9 (2.7) | 85.6 (3.1) | < 0.0001 |
| Sodium | 136.9 (1.2) | 136.9 (1.5) | 136.1 (1.7) | 139.7 (2.0) | 140.4 (2.4) | 0.345 |
| Potassium | 4.59 (0.12) | 4.55 (0.13) | 4.43 (0.14) | 4.67 (0.16) | 4.67 (0.20) | 0.382 |
| Calcium | 87.4 (1.5) | 84.6 (2.2) | 88.1 (1.9) | 89.0 (2.6) | 88.0 (2.8) | 0.558 |
| Haemoglobin | 10.2 (0.6) | 10.0 (0.7) | 9.6 (0.7) | 10.1 (0.8) | 11.1 (0.9) | 0.090 |
| TCMH | 30.2 (1.4) | 30.4 (1.6) | 32.2 (1.7) | 31.4 (1.9) | 32.0 (2.7) | 0.535 |
| VGM | 82.1 (2.1) | 78.8 (2.7) | 85.9 (2.9) | 84.9 (3.4) | 91.0 (4.5) | 0.051 |
| Phosphate | 45.4 (3.0) | 40.7 (5.3) | 41.9 (4.0) | 45.9 (5.5) | 40.4 (5.3) | 0.624 |
| Uric acid | 78.3 (3.9) | 67.6 (5.4) | 70.1 (5.1) | 68.3 (7.2) | 65.4 (8.2) | 0.034 |
| Albumin | 30.5 (2.4) | 35.3 (3.0) | 27.8 (3.3) | 30.5 (4.1) | 37.0 (7.3) | 0.125 |
| Total cholesterol | 2.4 (0.2) | 2.0 (0.2) | 1.8 (0.3) | 1.9 (0.3) | 2.6 (0.4) | 0.036 |
| HDL cholesterol | 0.51 (0.06) | 0.36 (0.19) | 0.30 (0.15) | 0.44 (0.27) | 0.53 (0.24) | 0.685 |
| Triglycerides | 1.7 (0.2) | 1.3 (0.4) | 1.6 (0.3) | 1.5 (0.4) | 1.4 (0.4 | 0.648 |
Estimates are mean and standard error of the mean, and are adjusted for age, sex, diabetes, hypertension smoking alcohol consumption, HIV status SBP Systolic blood pressure, DPB Diastolic blood pressure, eGFR Estimated Glomerular filtration rate, MCH Mean corpuscular haemoglobin, MCV Mean corpuscular volume, HDL High density lipoprotein, LDL Low density lipoprotein