Table 1.
Hemodynamic characteristics and organ perfusion at baseline, onset of cardiogenic shock, and after 30 min of Impella CP support
| Variable | Baseline | Cardiogenic shock | Impella 30 min |
|---|---|---|---|
| Mean (95% CI) | Mean (95% CI) | Mean (95% CI) | |
| Stroke work (mmHg × mL) | 4853 (3906, 5801) | 703 (350, 1056) | 980 (619, 1340) |
| Potential energy2 (mmHg × mL) | 4290 (2887, 5694) | 4567 (2973, 6161) | 2690 (2019, 3361) |
| PVA1 (mmHg × mL) | 9143 (7406, 10,880) | 5270 (3468, 7072) | 3670 (2780, 4560) |
| Heart rate (min−1) | 82 (75, 89) | 81 (75, 87) | 75 (69, 82) |
| LV work2 103 × (mmHg × mL)/min | 751.7 (595.2, 906.1) | 430.3 (271.3, 589.2) | 274.2 (206.9, 341.5) |
| Ees3 (mmHg/mL) | 1.42 (1.06, 1.79) | 0.40 (0.3, 0.5) | 0.74 (0.57, 0.92) |
| LVEDV4 (mL) | 156.1 (133, 179) | 188.8 (154, 224) | 125.2 (108, 142) |
| LVEDP5 (mmHg) | 16 (12.7, 19.2) | 22 (19.7, 24.8) | 19 (15, 22) |
| LVESV6 (mL) | 91.1 (69, 113.2) | 162.7 (130.2, 195.2) | 97 (82.4, 111.5) |
| LVESP7 (mmHg) | 104.87 (91.4, 118.3) | 58.35 (48.8, 67.9) | 61.65 (50.5, 72.9) |
| Mean arterial pressure, (mmHg) | 79 (71, 88) | 39 (30, 48) | 61 (51, 72) |
| Right atrial pressure (mmHg) | 9 (7, 11) | 14 (10, 17) | 12 (9, 14) |
| Mean pulmonary arterial pressure (mmHg) | 21 (19, 24) | 25 (21, 29) | 24 (20, 28) |
| Arterial lactate (mmol/L) | 1.49 (1.05, 1.94) | 2.1 (1.67, 2.51) | 2.22 (1.65, 2.79) |
| Mixed venous oxygen saturation (%) | 76 (69, 82) | 37 (30, 44) | 55 (47, 64) |
| Renal venous oxygen saturation (%) | 89 (85, 92) | 58 (42, 75) | 73 (62, 85) |
| Cerebral venous oxygen saturation (%) | 79 (73, 85) | 45 (35, 55) | 59 (48, 71) |
| Hemoglobin (mmol/L) | 6.4 (5.7, 7.1) | 5.6 (5.1, 6.2) | 6.1 (5.6, 6.6) |
Data are presented as mean and (95% CI). Abbreviations: PVA1 pressure volume area, LV work2 left ventricular work equals heart rate × pressure volume area, Ees3 left ventricular elastance, LVEDV4 left ventricular end-diastolic volume, LVEDP5 left ventricular end-diastolic pressure, LVESV6 left ventricular end-systolic volume, LVESP7 left ventricular end-systolic pressure