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. 2019 Apr 1;100(5):793–803. doi: 10.1099/jgv.0.001254

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© 2019 The Authors

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Fig. 4. — Amino acid variants of the complete S gene of strain YAK/HY24/CH/2017. The figures in the boxes indicate amino acid change sites in strain YAK/HY24/CH/2017 compared with the other 150 available BCoV S sequences in the GenBank database and 12 BCoV S sequences cloned by our laboratory (MH810151–MH810162). (a) Amino acid variants in the S1 subunit of strain YAK/HY24/CH/2017. (b) Amino acid variants in the S2 subunit of strain YAK/HY24/CH/2017. HP, the first hydrophobic domain of the S2 subunit; HR, hypervariable region; HR-N and HR-C, the heptad repeats; PC, proteolytic cleavage region; RBD, receptor-binding domain; S1A and S1B, the immune reactive domain; SP, signal peptide.