Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic overview of the targeted RNA recombination principle and the donor plasmids used in the present study. (a) Schematic overview of the targeted RNA recombination method to generate recombinant rIBV-wt [10]. IBV sequences are in blue and murine hepatitis virus (MHV) sequences are in red. (b) Schematic layout of the donor plasmids pIBV-Δ3a, pIBV-Δ3b, pIBV-Δ5a or pIBV-Δ5b used in targeted RNA recombination to generate rIBV-Δ3a, rIBV-Δ3b, rIBV-Δ5a and rIBV-Δ5b, respectively.
