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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Prog Mater Sci. 2019 Jul 17;106:100589. doi: 10.1016/j.pmatsci.2019.100589

Figure 2.8:

Figure 2.8:

In SELEX, aptamer libraries are filtered for specific binding to an analyte or surface, and are then amplified by RT-PCR. Following amplification, the process can be iterated (i.e. to arrive on consensus high-affinity ligands), or sequenced (i.e. to characterize the output) Reprinted by permission from (155) published by Elsevier.