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. 2009 Apr 15;2009(2):CD001290. doi: 10.1002/14651858.CD001290.pub2

Brown 2006.

Methods STUDY DESIGN: Parallel group 
 LOCATION, NUMBER OF CENTRES: USA, 1 centre 
 DURATION OF STUDY: 6 months
No blinding of outcome assessor
Participants N SCREENED: 771 
 N RANDOMISED: 129 
 M = Not reported 
 F = Not reported 
 BASELINE DETAILS: Primary care physician: 87%; Asthma action plan: 23%; Spacer: 57%; ICS: 78%; PEF meter: 44%; 37% were African American, 56% had moderate‐to‐severe persistent asthma, 78% on ICS at baseline 
 INCLUSION CRITERIA: Children or adults; asthma exacerbation presenting on ED visit, have had asthma symptoms in the prior 2 weeks, or a previous hospitalisation or ED visit in the past year 
 EXCLUSION CRITERIA: Not described
Interventions EDUCATION GROUP: Conducted by trained asthma educators and included a facilitated office visit with patient and primary care provider within 2 to 4 weeks of enrolment, a home‐visit 2 to 4 weeks thereafter
Setting: Home
CONTROL GROUP: Usual care, including instructions in inhaler device technique, written discharge instructions and planned follow up
TREATMENT PERIOD: 2 visits up to 8 weeks post‐enrolment 
 FOLLOW‐UP PERIOD: 6 months
Outcomes Urgent asthma visit; treatment compliance; withdrawals
Notes 39% in intervention group did not comply with any aspect of planned educational programme
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Low risk Computer‐generated random number sequences
Allocation concealment? Low risk Sealed envelopes
Incomplete outcome data addressed? 
 All outcomes Unclear risk Described as intention‐to‐treat; no explicit description of how this population was composed